Lyophilization of Liposomal Formulations: Still Necessary, Still Challenging

Is Mutagenesis still challenging?

Mutagenesis is a well-known benchmark machine learning dataset. In this paper we present an overview of results for various methods applied to this dataset. In particular, we present a new result based on an ensemble method using Aleph-generated theories in which we achieve a cross-validated accuracy of 95.8%. This is the highest predictive accuracy to date, and we believe begs the question “Is...

Pathology: is it still necessary?

One may wonder what may be the reasons to ask this apparently odd question. Undoubtedly, the main concern is that we are still far away from being able to precisely identify the target population of patients for tailored interventions. It has been repeatedly shown by the results of large clinical trials that the benefit of new therapeutic approaches is relatively small, and that it is most like...

Fetal mild ventriculomegaly: still a challenging problem.

Ventriculomegaly (VM) is defined as an enlargement of the lateral ventricles of the developing fetal brain. Measurement of the size of the fetal cerebral lateral ventricles is recommended as part of the fetal scan routinely performed during the second trimester to screen for fetal anomalies. The measurement is done at the level of the atria of the lateral ventricles filled by the echogenic chor...

Is breast self-examination still necessary?

Is antenatal screening for syphilis still necessary?